CCL3L1 gene-containing segmental duplications and polymorphisms in CCR5 affect risk of systemic lupus erythaematosus

Objectives: There is an enrichment of immune response genes that are subject to copy number variations (CNVs). However, there is limited understanding of their impact on susceptibility to human diseases. CC chemokine ligand 3 like-1 (CCL3L1) is a potent ligand for the HIV coreceptor, CC chemokine re...

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Autores:

Tipo de recurso:

Fecha de publicación:

2008

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22367

Acceso en línea:

https://doi.org/10.1136/ard.2007.078048
https://repository.urosario.edu.co/handle/10336/22367

Palabra clave:

Chemokine receptor CCR5
Macrophage inflammatory protein 1alpha
Adult
Antibody titer
Article
Cohort analysis
Controlled study
DNA polymorphism
Female
Gene duplication
Genetic risk
Genetic variability
Genotype phenotype correlation
Human
Lupus erythematosus nephritis
Major clinical study
Male
Priority journal
Systemic lupus erythematosus
Adult
Autoantibodies
Case-Control Studies
Chemokine CCL3
Female
Gene Dosage
Genetic Predisposition to Disease
Genotype
Humans
Kidney
Leukocytes
Logistic Models
Lupus Nephritis
Male
Middle Aged
Prospective Studies
Risk
Systemic
Differentiation
CCR5
CD
CD3
Genetic
Leukocyte
Myelomonocytic
Antigens
Antigens
Antigens
Chemotaxis
Lupus Erythematosus
Polymorphism
Receptors

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