Neuroprotective effects of gacyclidine after experimental photochemical spinal cord lesion in adult rats: Dose-window and time-window effects

The aim of this study was to evaluate the efficacy, optimal dose, and optimal time-window of gacyclidine, a novel N-methyl-D-aspartate (NMDA) receptor antagonist, in terms of its functional, histopathological, and electrophysiological effects after experimental spinal cord injury. The spinal cord of...

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Autores:

Tipo de recurso:

Fecha de publicación:

2000

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22409

Acceso en línea:

https://doi.org/10.1089/neu.2000.17.19
https://repository.urosario.edu.co/handle/10336/22409

Palabra clave:

Gacyclidine
N methyl dextro aspartic acid receptor blocking agent
Unclassified drug
Animal experiment
Animal model
Article
Controlled study
Dose response
Evoked somatosensory response
Locomotion
Male
Motor performance
Neuroprotection
Nonhuman
Rat
Spinal cord injury
Spinal cord lesion
Dose-window
Gacyclidine
N-methyl-d-aspartate
Photochemical lesion
Secondary injury
Spinal cord injury
Time-window

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