Mycobacterium tuberculosis surface protein Rv0227c contains high activity binding peptides which inhibit cell invasion

Mycobacterium tuberculosis surface proteins involved in target cell invasion may be identified as a strategy for developing subunit-based, chemically-synthesized vaccines. The Rv0227c protein was thus selected to assess its role in the invasion and infection of Mycobacterium tuberculosis target cell...

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Autores:
Tipo de recurso:
Fecha de publicación:
2012
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/22792
Acceso en línea:
https://doi.org/10.1016/j.peptides.2012.08.023
https://repository.urosario.edu.co/handle/10336/22792
Palabra clave:
Bacterial protein
Membrane protein
Protein rv0227c
Unclassified drug
Amino acid sequence
Animal experiment
Antibacterial activity
Article
Binding affinity
Bioinformatics
Cell invasion
Concentration response
Controlled study
Cytotoxicity
Experimental rabbit
Immunoelectron microscopy
Nonhuman
Phagocyte
Polymerase chain reaction
Priority journal
Protein analysis
Protein binding
Protein localization
Spectroscopy
Tuberculosis
Western blotting
Bacterial proteins
Bacterial vaccines
Cell survival
Humans
Membrane proteins
Mycobacterium tuberculosis
Peptides
Reverse transcriptase polymerase chain reaction
Structure-activity relationship
U937 cells
Mycobacterium tuberculosis
Invasion
Mycobacterium tuberculosis
Receptor-ligand interaction
Rv0227c protein
Synthetic peptide
Vaccine
western
immunoelectron
drug
cultured
Blotting
Dose-response relationship
Microscopy
Tumor cells
Rights
License
Abierto (Texto Completo)