3D Analysis of the TCR/pMHCII Complex Formation in Monkeys Vaccinated with the First Peptide Inducing Sterilizing Immunity against Human Malaria

T-cell receptor gene rearrangements were studied in Aotus monkeys developing high antibody titers and sterilizing immunity against the Plasmodium falciparum malaria parasite upon vaccination with the modified synthetic peptide 24112, which was identified in the Merozoite Surface Protein 2 (MSP-2) an...

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Autores:

Tipo de recurso:

Fecha de publicación:

2010

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/8806

Acceso en línea:

https://doi.org/10.1371/journal.pone.0009771
http://repository.urosario.edu.co/handle/10336/8806

Palabra clave:

Receptor de células T
Mhc Clase-ii
Monos del nuevo mundo
Las células rojas de la sangre
Plasmodium falciparum
Estructura cristalina
Hla-dr4 Dra-asterisco-0101
Aotus-nancymaae
Aminoácidos
Diversidad
Enfermedades
Malaria
Plasmodio
Enfermedades autoinmunes
Inmunología
T-cell-receptor
Mhc Class-ii
New-world Monkeys
Red-blood-cells
Plasmodium-falciparum
Crystal-structure
Hla-dr4 Dra-asterisk-0101
Aotus-nancymaae
Amino-acids
Diversity

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