Behavioral abnormalities in female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil

Vaccine adjuvants and vaccines may induce autoimmune and inflammatory manifestations in susceptible individuals. To date most human vaccine trials utilize aluminum (Al) adjuvants as placebos despite much evidence showing that Al in vaccine-relevant exposures can be toxic to humans and animals. We so...

Full description

Autores:
Tipo de recurso:
Fecha de publicación:
2017
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/24278
Acceso en línea:
https://doi.org/10.1007/s12026-016-8826-6
https://repository.urosario.edu.co/handle/10336/24278
Palabra clave:
Aluminum hydroxide
Autoantibody
Pertussis toxin
Wart virus vaccine
Aluminum hydroxide
Autoantibody
Capsid protein
Immunological adjuvant
Oncoprotein
Pharmaceutical vehicles and additives
Virus antibody
Virus antigen
Wart virus vaccine
Animal model
Animal tissue
Article
Behavior disorder
Brain perfusion
Cognition
Controlled study
Enzyme inhibition assay
Enzyme linked immunosorbent assay
Female
Forced swim test
Hippocampus
Immunohistochemistry
Locomotion
Microglia
Mouse
Nonhuman
Priority journal
Staircase test
Visual memory
Animal
Animal behavior
Blood
C57bl mouse
Drug effects
Immunology
Recognition
Swimming
Aluminum hydroxide
Animals
Autoantibodies
Capsid proteins
Female
Human papillomavirus recombinant vaccine quadrivalent, types 6, 11, 16, 18
Locomotion
Recognition (psychology)
Swimming
Aluminum
Asia syndrome
Autoantibodies
Autoimmunity
Gardasil
Neuroinflammation
human papillomavirus
viral
viral
viral
pharmaceutic
inbred c57bl
immunologic
animal
Hpv l1 protein
Adjuvants
Adjuvants
Antibodies
Antigens
Behavior
Mice
Oncogene proteins
Rights
License
Abierto (Texto Completo)