The molecular complexity of primary ovarian insufficiency aetiology and the use of massively parallel sequencing

Primary ovarian insufficiency (POI) is a frequently occurring pathology, leading to infertility. Genetic anomalies have been described in POI and mutations in numerous genes have been definitively related to the pathogenesis of the disease. Some studies based on next generation sequencing (NGS) have...

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Autores:

Tipo de recurso:

Fecha de publicación:

2018

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22605

Acceso en línea:

https://doi.org/10.1016/j.mce.2017.07.021
https://repository.urosario.edu.co/handle/10336/22605

Palabra clave:

Gene expression
Gene mutation
Human
Massively parallel sequencing
Meiosis
Next generation sequencing
Nonhuman
Ovary follicle development
Ovulation
Pathogenesis
Premature ovarian failure
Priority journal
Review
Sequence analysis
Sex determination
Female
Genetics
High throughput sequencing
Metabolism
Ovary follicle
Premature ovarian failure
Procedures
Sex determination process
Female
High-throughput nucleotide sequencing
Humans
Meiosis
Ovarian follicle
Ovulation
Primary ovarian insufficiency
Sex determination processes
Female infertility
Molecular aetiology
Next generation sequencing
Primary ovarian insufficiency

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