Mycobacterium tuberculosis PE9 protein has high activity binding peptides which inhibit target cell invasion

PE/PPE proteins are involved in several processes during Mycobacterium tuberculosis (Mtb) infection of target cells; studying them is extremely interesting as they are the only ones from the Mycobacterium genus, they abound in pathogenic species such as Mtb and their function remains yet unknown. Th...

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Autores:

Tipo de recurso:

Fecha de publicación:

2016

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/24335

Acceso en línea:

https://doi.org/10.1016/j.ijbiomac.2015.12.081
https://repository.urosario.edu.co/handle/10336/24335

Palabra clave:

Bacterial protein
Pe9 protein
Unclassified drug
Bacterial protein
Peptide
Protein binding
Article
Bacterial strain
Cell invasion
Circular dichroism
Controlled study
Crystal structure
Mycobacterium tuberculosis
Nonhuman
Protein binding
Protein expression
Protein localization
Protein secondary structure
Protein targeting
Surface property
A-549 cell line
Amino acid sequence
Biology
Chemistry
Enzyme specificity
Epithelium cell
Genetic transcription
Genetics
Human
Macrophage
Metabolism
Microbiology
Molecular model
Mycobacterium tuberculosis
Physiology
Protein conformation
Protein transport
A549 cells
Amino acid sequence
Bacterial proteins
Computational biology
Epithelial cells
Humans
Macrophages
Mycobacterium tuberculosis
Peptides
Protein binding
Protein conformation
Protein transport
Substrate specificity
Pe9 protein
Synthetic peptide
Tuberculosis
molecular
genetic
Models
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