The effector of hedgehog signaling, the transcription factor GLI1: novel regulatory mechanisms and role in tamoxifen treatment

In Chapter I, we describe the characterization of an RNA transcript from the antisense strand of the GLI1 gene, termed GLI1AS, with no potential to code for a long protein, which acts as a negative regulator of GLI1 expression. We provide evidence for capping and polyadenylation of this antisense RN...

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Autores:

Tipo de recurso:

Fecha de publicación:

2017

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

spa

OAI Identifier:

oai:repository.urosario.edu.co:10336/13783

Acceso en línea:

https://doi.org/10.48713/10336_13783
http://repository.urosario.edu.co/handle/10336/13783

Palabra clave:

antisense RNA regulation
Hedgehog pathway
GLI1
Enfermedades
Proteína con Dedos de Zinc GLI1
Células Madre
Neoplasias de la Mama
Estudios de evaluación
HH signaling pathway
GLI1
RNA antisense regulation

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Abierto (Texto completo)