Pigment epithelium-derived factor: Clinical significance in estrogen-dependent tissues and its potential in cancer therapy

Pigment epithelium-derived factor (PEDF) is a glycoprotein that belongs to the family of noninhibitory serpins. The broad spectrum of PEDF biological activity is evident when considering its effects in promoting cell survival and proliferation, as well as its antiangiogenic, antitumor, and antimetas...

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Autores:

Tipo de recurso:

Fecha de publicación:

2015

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22193

Acceso en línea:

https://repository.urosario.edu.co/handle/10336/22193

Palabra clave:

Estrogen
Pigment epithelium derived factor
Angiogenesis
Article
Cancer therapy
Cell cycle regulation
Cell proliferation
Cell survival
Cellular distribution
Endometrium
Human
Mammary gland
Nuclear localization signal
Oxidative stress
Protein expression
Publication
Senescence
Signal transduction
Anti-tumorigenesis
Antiangiogenesis
Estrogen receptors
Estrogens
Hormonal regulation
Pedf
Synthetic peptides

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