Changing ABRA protein peptide to fit into the HLA-DRbeta1*0301 molecule renders it protection-inducing
The Plasmodium falciparum acidic–basic repeat antigen represents a potential malarial vaccine candidate. One of this protein’s high activity binding peptides, named 2150 (161KMNMLKENVDYIQKNQNLFK180), is conserved, non-immunogenic, and non-protection-inducing. Analogue peptides whose critical binding...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2004
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/26036
- Acceso en línea:
- https://doi.org/10.1016/j.bbrc.2004.07.086
https://repository.urosario.edu.co/handle/10336/26036
- Palabra clave:
- ABRA protein
Peptide analogues
Vaccine candidate
Malaria
Conformation
NMR
- Rights
- License
- Restringido (Acceso a grupos específicos)