Specific Binding Peptides from Rv3632: A Strategy for Blocking Mycobacterium tuberculosis Entry to Target Cells?

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (Mtb, i.e., the aetiological agent); the WHO has established this disease as high priority due to its ensuing mortality. Mtb uses a range of mechanisms for preventing its elimination by an infected host; new, viable alternati...

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Autores:
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23528
Acceso en línea:
https://doi.org/10.1155/2019/8680935
https://repository.urosario.edu.co/handle/10336/23528
Palabra clave:
Arginine
Epitope
Glycine
Peptide
Synthetic peptide
Threonine
Bacterial protein
Peptide
Protein binding
A-549 cell line
Animal cell
Article
Bacterial membrane
Bioinformatics
Carboxy terminal sequence
Circular dichroism
Concentration response
Female
Host pathogen interaction
Latent tuberculosis
Lung alveolus epithelium cell
Mortality
Mouse
Mycobacterium tuberculosis
Nonhuman
Protein secondary structure
Target cell
U-937 cell line
Amino acid sequence
Biology
Cell membrane
Cell wall
Chemistry
Genetic transcription
Genetics
Human
Isolation and purification
Metabolism
Molecular model
Mycobacterium tuberculosis
A549 cells
Amino acid sequence
Bacterial proteins
Cell membrane
Cell wall
Circular dichroism
Computational biology
Host-pathogen interactions
Humans
Mycobacterium tuberculosis
Peptides
Protein binding
U937 cells
genetic
secondary
molecular
Models
Protein structure
Transcription
Rights
License
Abierto (Texto Completo)