Rh1 high activity binding peptides inhibit high percentages of Plasmodium falciparum FVO strain invasion

Identifying the minimal functional regions of the proteins which the malaria parasite uses when invading its host cells constitutes the first and most important approach in an effective design for a chemically synthesised, multi-antigen, multi-stage, subunit-based vaccine. This work has been aimed a...

Full description

Autores:
Tipo de recurso:
Fecha de publicación:
2013
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23460
Acceso en línea:
https://doi.org/10.1016/j.vaccine.2013.01.052
https://repository.urosario.edu.co/handle/10336/23460
Palabra clave:
Amino acid
Membrane receptor
Protein
Rh1 protein
Unclassified drug
Alpha helix
Article
Cell invasion
Controlled study
Erythrocyte
Gene expression
In vitro study
Nonhuman
Plasmodium falciparum
Priority journal
Protein binding
Protein polymorphism
Reticulocyte
Schizont
Amino acid sequence
Erythrocytes
Host-pathogen interactions
Humans
Malaria
Malaria vaccines
Molecular sequence data
Peptides
Plasmodium falciparum
Protein structure, secondary
Protein structure, tertiary
Protozoan proteins
Schizonts
Malaria
Plasmodium falciparum
Reticulocyte binding-like
Synthetic peptide
subunit
Vaccines
Rights
License
Abierto (Texto Completo)