Global phylogeny of Mycobacterium tuberculosis based on single nucleotide polymorphism (SNP) analysis: Insights into tuberculosis evolution, phylogenetic accuracy of other DNA fingerprinting systems, and recommendations for a minimal standard SNP set

We analyzed a global collection of Mycobacterium tuberculosis strains using 212 single nucleotide polymorphism (SNP) markers. SNP nucleotide diversity was high (average across all SNPs, 0.19), and 96% of the SNP locus pairs were in complete linkage disequilibrium. Cluster analyses identified six dee...

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Autores:
Tipo de recurso:
Fecha de publicación:
2006
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/21927
Acceso en línea:
https://doi.org/10.1128/JB.188.2.759-772.2006
https://repository.urosario.edu.co/handle/10336/21927
Palabra clave:
Enfermedades
Evolución & genética
Microbiología
Controlled study
Genetic variability
Humans
Mycobacterium tuberculosis
Bacteria (microorganisms)
Mycobacterium tuberculosis
DNA fingerprinting
DNA sequence
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