PTPN22 C1858T polymorphism in Colombian patients with autoimmune diseases

A functional single nucleotide polymorphism (SNP) C1858T in the protein tyrosine phosphatase nonreceptor 22 (PTPN22) gene encoding an intracellular phosphatase with negative regulatory effects on T-cell activation is associated with some autoimmune diseases in Caucasians. Taking into account firstly...

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Autores:

Tipo de recurso:

Fecha de publicación:

2005

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/24138

Acceso en línea:

https://doi.org/10.1038/sj.gene.6364261
https://repository.urosario.edu.co/handle/10336/24138

Palabra clave:

Protein tyrosine phosphatase
Protein tyrosine phosphatase nonreceptor 22
Unclassified drug
Article
Autoimmune disease
Autoimmunity
Caucasian
Colombia
Controlled study
Dna polymorphism
Gene frequency
Gene replication
Genetic code
Genotype
Human
Immunogenetics
Insulin dependent diabetes mellitus
Intracellular space
Major clinical study
Phenotype
Priority journal
Real time polymerase chain reaction
Rheumatoid arthritis
Risk factor
Single nucleotide polymorphism
Sjoegren syndrome
Systemic lupus erythematosus
T lymphocyte activation
Adult
Aged
Alleles
Autoimmune diseases
Colombia
European continental ancestry group
Female
Humans
Male
Middle aged
Protein-tyrosine-phosphatase
Sjogren's syndrome
Colombia
Diabetes mellitus
Ptpn22
Rheumatoid arthritis
Sjögren's syndrome
Systemic lupus erythematosus
single nucleotide
rheumatoid
type 1
systemic
Arthritis
Diabetes mellitus
Lupus erythematosus
Polymorphism

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