Influence of Two Major Toxoplasma Gondii Virulence Factors (ROP16 and ROP18) on the Immune Response of Peripheral Blood Mononuclear Cells to Human Toxoplasmosis Infection

Toxoplasma gondii ROP16 and ROP18 proteins have been identified as important virulence factors for this parasite. Here, we describe the effect of ROP16 and ROP18 proteins on peripheral blood mononuclear cells (PBMCs) from individuals with different clinical status of infection. We evaluated IFN-?, I...

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Autores:

Tipo de recurso:

Fecha de publicación:

2019

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/24080

Acceso en línea:

https://doi.org/10.3389/fcimb.2019.00413
https://repository.urosario.edu.co/handle/10336/24080

Palabra clave:

Gamma interferon
Interleukin 10
Interleukin 1beta
Purinergic p2y2 receptor
Rop16 protein
Rop18 protein
Stat3 protein
Stat6 protein
Toll like receptor 9
Unclassified drug
Virulence factor
Adult
Article
Asymptomatic infection
Clinical article
Controlled study
Cytokine release
Enzyme linked immunosorbent assay
Eye infection
Female
Gene expression
Gene knockout
Human
Human cell
Immune response
Inflammation
Male
Nonhuman
Ocular toxoplasmosis
Ophthalmoscopy
Parasite virulence
Peripheral blood mononuclear cell
Protein expression
Protein phosphorylation
Single nucleotide polymorphism
Tachyzoite
Toxoplasma gondii
Toxoplasmosis
Western blotting
Cytokines
Ocular toxoplasmosis
Peripheral blood mononuclear cells
Polymorphisms
Rop16 protein
Rop18 protein
Toxoplasma

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