Based on HLA-DR?1* allele binding specificities, striking differences in distance and tcr contacting residue orientation can be observed in modified protection-inducing malarial synthetic peptides

An anti-malarial vaccine is urgently needed, especially against P. falciparum which causes 2 to 3 million deaths each year, mostly in Sub-Saharan African children. This vaccine should contain molecules from the parasites different developmental stages due to the parasites remarkable complexity and g...