Effect of etodolac on methotrexate pharmacokinetics in patients with rheumatoid arthritis

OBJECTIVE: To determine if the pharmacokinetics of methotrexate (MTX) is modified by the coadministration of etodolac. METHODS: MTX (10 mg) was administered intramuscularly in the absence and presence of steady state levels of etodolac in 19 patients with rheumatoid arthritis. MTX levels were assaye...

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Autores:
Tipo de recurso:
Fecha de publicación:
1991
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/27572
Acceso en línea:
https://repository.urosario.edu.co/handle/10336/27572
Palabra clave:
Pharmacokinetics of methotrexate (MTX)
Etodolac
Liquid chromatography
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