Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility

Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins (CFHR1-CFHR5) within the chromosome 1q32 locus linked to SLE, have been associa...

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Autores:

Tipo de recurso:

Fecha de publicación:

2011

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/8779

Acceso en línea:

https://doi.org/10.1371/journal.pgen.1002079
http://repository.urosario.edu.co/handle/10336/8779

Palabra clave:

Enfermedades
Genes
Genética
Lupus eritematoso sistémico
Inmunología
Complement factor H
Complement regulator factor H related protein 1
Complement regulator factor H related protein 2
Complement regulator factor H related protein
Plasma protein
Unclassified drug
Bladder tumor associated antigen
Complement factor H
Tumor antigen
Tumor marker

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