TIRAP (MAL) S180L polymorphism is a common protective factor against developing tuberculosis and systemic lupus erythematosus

Background and aim: The involvement of Toll-like receptor (TLR)-mediated pathways in infectious and autoimmunity has been suggested. The MyD88 adaptor-like (Mal) protein, also known as the TIR domain-containing adaptor protein (TIRAP), is implicated in the TLR2- and TLR4-mediated MyD88-dependent sig...

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Autores:

Tipo de recurso:

Fecha de publicación:

2008

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/24308

Acceso en línea:

https://doi.org/10.1016/j.meegid.2008.03.001
https://repository.urosario.edu.co/handle/10336/24308

Palabra clave:

Adaptor protein
Leucine
Toll like receptor domain containing adaptor protein
Adult
Allele
Article
Autoimmune disease
Case control study
Colombia
Confidence interval
Controlled study
Family
Female
Gene sequence
Genetic polymorphism
Genetic susceptibility
Genotype
Human
Innate immunity
Insulin dependent diabetes mellitus
Major clinical study
Male
Polymerase chain reaction
Priority journal
Protection
Restriction fragment length polymorphism
Rheumatoid arthritis
Sjoegren syndrome
Systemic lupus erythematosus
Tuberculosis
Adult
Case-control studies
Colombia
Female
Gene frequency
Genotype
Humans
Male
Membrane glycoproteins
Middle aged
Tuberculosis
Mal
Rheumatoid arthritis
Sjögren's syndrome
Systemic lupus erythematosus
Tirap
Tuberculosis
Type 1 diabetes mellitus
systemic
interleukin-1
genetic
Lupus erythematosus
Polymorphism
Receptors

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