Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus

Leptin is abnormally elevated in the plasma of patients with systemic lupus erythematosus (SLE), where it is thought to promote and/or sustain pro-inflammatory responses. Whether this association could reflect an increased genetic susceptibility to develop SLE is not known, and studies of genetic as...

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Autores:

Tipo de recurso:

Fecha de publicación:

2015

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23683

Acceso en línea:

https://doi.org/10.1016/j.clim.2015.09.007
https://repository.urosario.edu.co/handle/10336/23683

Palabra clave:

Leptin
Leptin
African american
Article
Controlled study
Dna determination
East asian
European american
Gene
Genetic association
Genetic risk
Genetic susceptibility
Genotype
Ghsr gene
Hispanic
Human
Inflammation
Lep gene
Lepr gene
Major clinical study
Pparg gene
Priority journal
Single nucleotide polymorphism
Systemic lupus erythematosus
Case control study
Genetic predisposition
Genetics
Single nucleotide polymorphism
Systemic lupus erythematosus
Case-control studies
Genetic predisposition to disease
Genotype
Humans
Leptin
Gene polymorphisms
Leptin pathway
Systemic lupus erythematosus
systemic
single nucleotide
Lupus erythematosus
Polymorphism

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