Genetic Influence of PTPN22 R620W Polymorphism in Tuberculosis

The PTPN22 gene codes for an intracellular lymphoid-specific phosphatase (Lyp) that has a negative regulatory effect on T-cell activation. Because Lyp is an important molecule involved in the inflammatory response, and its levels are increased in cells that participate in the immune response against...

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Autores:

Tipo de recurso:

Fecha de publicación:

2005

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/24216

Acceso en línea:

https://doi.org/10.1016/j.humimm.2005.11.008
https://repository.urosario.edu.co/handle/10336/24216

Palabra clave:

Protein
Protein tyrosine phosphatase nonreceptor 22 protein
Unclassified drug
Protein tyrosine phosphatase
Protein tyrosine phosphatase lyp
Protein-tyrosine phosphatase lyp
Adult
Antigen recognition
Article
Autoimmunity
Confidence interval
Controlled study
Dna polymorphism
Female
Gene frequency
Genetic analysis
Genetic code
Genetic predisposition
Genetic risk
Heredity
Human
Immune system
Lung tuberculosis
Major clinical study
Male
Mycobacterium tuberculosis
Priority journal
Randomization
Risk factor
Tuberculin test
Case control study
Colombia
Genetics
Immunology
Lung tuberculosis
Middle aged
Single nucleotide polymorphism
Adult
Case-control studies
Colombia
Female
Genetic predisposition to disease
Humans
Male
Middle aged
Mycobacterium tuberculosis
Protein-tyrosine-phosphatase
Autoimmunity
Delayed-type hypersensitivity
Ptpn22
Tuberculin skin test
Tuberculosis
pulmonary
single nucleotide
Polymorphism
Tuberculosis

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