Semi-empirical quantum evaluation of peptide – MHC class II binding

Peptide presentation by the major histocompatibility complex (MHC) is a key process for triggering a specific immune response. Studying peptide-MHC (pMHC) binding from a structural-based approach has potential for reducing the costs of investigation into vaccine development. This study involved usin...

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Autores:

Tipo de recurso:

Fecha de publicación:

2017

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23651

Acceso en línea:

https://doi.org/10.1016/j.cplett.2016.12.015
https://repository.urosario.edu.co/handle/10336/23651

Palabra clave:

Bins
Molecules
Peptides
Quantum chemistry
Binding interaction
Experimental values
FMO-DFTB
HLA-DR
Major histocompatibility complex
Quantum chemistry methods
Receptor-ligand interactions
Vaccine development
Binding energy
FMO-DFTB
HLA-DR
PM7
Receptor-ligand interactions

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