A Sequence in Subdomain 2 of DBL1a of Plasmodium falciparum Erythrocyte Membrane Protein 1 Induces Strain Transcending Antibodies

Immunity to severe malaria is the first level of immunity acquired to Plasmodium falciparum. Antibodies to the variant antigen PfEMP1 (P. falciparum erythrocyte membrane protein 1) present at the surface of the parasitized red blood cell (pRBC) confer protection by blocking microvascular sequestrati...

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Autores:

Tipo de recurso:

Fecha de publicación:

2013

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/8765

Acceso en línea:

https://doi.org/10.1371/journal.pone.0052679
http://repository.urosario.edu.co/handle/10336/8765

Palabra clave:

Malaria
Inmunología
PfEMP1
Plasmodium
Erythrocyte membrane protein 1
protozoan
Protein antibody
Molecular
Preschool
Strain transcending antibody
Unclassified drug
Amino acid sequence
Antigen antibody reaction
Antigen binding
Child
Disease severity
Erythrocyte
Flow cytometry
Immunofluorescence test
In vitro study
Plasmodium falciparum
Preschool child
Protein binding
Protein domain
Protein motif
Amino acid motifs
Erythrocytes
Immunoglobulin g
Molecular sequence data
Plasmodium falciparum
Plasmodium falciparum

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