Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest

Many environmental and physiological stresses are chronic. Thus, cells are constantly exposed to diverse types of genotoxic insults that challenge genome stability, including those that induce oxidative DNA damage. However, most in vitro studies that model cellular response to oxidative stressors em...

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Autores:
Tipo de recurso:
Fecha de publicación:
2016
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/27532
Acceso en línea:
https://doi.org/10.1016/j.redox.2016.07.004
https://repository.urosario.edu.co/handle/10336/27532
Palabra clave:
ROS
Genotoxicity
DNA damage response
Up-regulation of DNA repair genes
G2/M arrest
Adaptation
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