Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: Evidence for replication and gene-gene interaction

Objective. Recent studies have identified several common genes associated with multiple autoimmune diseases that support the hypothesis of the presence of shared or general autoimmunity genes. However, most of this work has been performed in populations of white origin. The main objectives of this s...

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Autores:

Tipo de recurso:

Fecha de publicación:

2011

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22452

Acceso en línea:

https://doi.org/10.3899/jrheum.110199
https://repository.urosario.edu.co/handle/10336/22452

Palabra clave:

Adult
Allele
Article
Autoimmune disease
C8orf13 blk gene
Cd226 gene
Chromosome 18q
Chromosome 8p
Colombian
Controlled study
Ethnic group
Ethnicity
Female
Gene
Gene interaction
Gene locus
Gene mutation
Genetic association
Genetic variability
Genotype phenotype correlation
Human
Il2 gene
Il21 gene
Insulin dependent diabetes mellitus
Major clinical study
Male
Mmel1 gene
Multiple sclerosis
Mutational analysis
Population genetics
Priority journal
Rheumatoid arthritis
Single nucleotide polymorphism
Case-control studies
Colombia
Female
Genetic association studies
Genetic loci
Genetic predisposition to disease
Genetic variation
Genome-wide association study
Hispanic americans
Humans
Male
Gene-gene interaction
Genetic association
Latin america
Rheumatoid arthritis
genetic
rheumatoid
Arthritis
Epistasis

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