Trans-Ancestral Studies Fine Map the SLE-Susceptibility Locus TNFSF4

We previously established an 80 kb haplotype upstream of TNFSF4 as a susceptibility locus in the autoimmune disease SLE. SLE-associated alleles at this locus are associated with inflammatory disorders, including atherosclerosis and ischaemic stroke. In Europeans, the TNFSF4 causal variants have rema...

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Autores:

Tipo de recurso:

Fecha de publicación:

2013

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/8829

Acceso en línea:

https://doi.org/10.1371/journal.pgen.1003554
http://repository.urosario.edu.co/handle/10336/8829

Palabra clave:

Evolución & genética
Anticuerpos
Alelos
Genética
Inmunología
Autoantibody
OX40 ligand
Transcription factor RelA
African American
Allele
American Indian
Antibody production
Cell isolation

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