Differential regulation of AKT, MAPK and GSK3? during C2-ceramide-induced neuronal death
Evidence has implicated apoptosis as a mechanism underlying cell demise in diverse neurodegenerative diseases including Parkinson's disease (PD). Endogenous toxins and other stress signals activate the sphingomyelin pathway increasing the levels of ceramide, an important regulator of cell death...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2010
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/22659
- Acceso en línea:
- https://doi.org/10.1016/j.neuro.2010.08.001
https://repository.urosario.edu.co/handle/10336/22659
- Palabra clave:
- Ceramide
Glycogen synthase kinase 3beta
Mitogen activated protein kinase
Neurotrophin 3
Protein kinase b
Somatomedin c
Article
Cell culture
Cell line
Cell survival
Controlled study
Drug exposure
Enzyme activation
Enzyme inhibition
Enzyme phosphorylation
Enzyme regulation
Nerve cell necrosis
Neuroprotection
Priority journal
Animals
Cell death
Cell survival
Glycogen synthase kinase 3
Insulin-like growth factor i
Mice
Mitogen-activated protein kinases
Neurons
Neuroprotective agents
Proto-oncogene proteins c-akt
Sphingosine
Akt
Apoptosis
Cad cells
Ceramide
Gsk3?
Igf-1
Mapk
- Rights
- License
- Abierto (Texto Completo)