Expression of the major and pro-oncogenic H3K9 lysine methyltransferase SETDB1 in non-small cell lung cancer

SETDB1 is a key histone lysine methyltransferase involved in gene silencing. The SETDB1 gene is amplified in human lung cancer, where the protein plays a driver role. Here, we investigated the clinical significance of SETDB1 expression in the two major forms of human non-small cell lung carcinoma (N...

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Autores:

Tipo de recurso:

Fecha de publicación:

2019

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23638

Acceso en línea:

https://doi.org/10.3390/cancers11081134
https://repository.urosario.edu.co/handle/10336/23638

Palabra clave:

Histone lysine methyltransferase
Messenger rna
Setdb1 protein
Unclassified drug
Article
Controlled study
Disease association
Female
Gene
Human
Human tissue
Lung adenocarcinoma
Major clinical study
Male
Non small cell lung cancer
Pathology
Protein expression
Setdb1 gene
Smoking
Squamous cell lung carcinoma
Transcriptomics
Lysine methyltransferase
Meta-analysis
Non-small cell lung cancer
Setdb1/kmt1e

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