3D structure determination of STARP peptides implicated in P. falciparum invasion of hepatic cells

To block the different stages of Plasmodium falciparum invasion into human hepatocytes and red blood cells, we have focused on those proteins belonging to the pre-erythrocytic stage. One of these proteins is Sporozoite Threonine and Asparagine Rich Protein (STARP), which is a ligand used by P. falci...

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Autores:
Tipo de recurso:
Fecha de publicación:
2010
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23458
Acceso en línea:
https://doi.org/10.1016/j.vaccine.2010.05.025
https://repository.urosario.edu.co/handle/10336/23458
Palabra clave:
HLA DQB1 antigen
Malaria vaccine
Protozoal protein
Sporozoite threonine and asparagine rich protein
Unclassified drug
HLA DR antigen
HLA DRB1 antigen
Malaria vaccine
Parasite antigen
Protein binding
Protozoon antibody
Alpha helix
Amino acid sequence
Animal experiment
Animal model
Aotus
Article
Circular dichroism
Controlled study
Drug structure
Immunogenicity
Nonhuman
Nuclear Overhauser effect
Peptide synthesis
Plasmodium falciparum
Priority journal
Proton nuclear magnetic resonance
Sporozoite
Vaccine production
Animal
Antibody production
Blood
Chemistry
Human
Immunology
Liver cell
Malaria falciparum
Molecular genetics
Parasitology
Pathogenicity
Protein tertiary structure
Amino Acid Sequence
Animals
Antibody Formation
Aotus trivirgatus
Hepatocytes
HLA-DR Antigens
Humans
Malaria Vaccines
Molecular Sequence Data
Plasmodium falciparum
Protein Binding
Amino Acid Sequence
Animals
Antibody Formation
Aotus trivirgatus
Hepatocytes
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Malaria Vaccines
Molecular Sequence Data
Plasmodium falciparum
Protein Binding
1H NMR
Malaria vaccine
Sporozoite
Structure
Falciparum
Protozoan
Protozoan
Plasmodium falciparum
Falciparum
Tertiary
Tertiary
Protozoan
Protozoan
STARP antigen
Antibodies
Antigens
Malaria
Protein Structure
Antibodies
Antigens
Malaria
Protein Structure
Rights
License
Abierto (Texto Completo)