Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups

Objective T cells from patients with systemic lupus erythematosus (SLE) express increased amounts of PP2Ac, which contributes to decreased production of interleukin-2 (IL-2). Because IL-2 is important in the regulation of several aspects of the immune response, it has been proposed that PP2Ac contri...

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Autores:

Tipo de recurso:

Fecha de publicación:

2011

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22966

Acceso en línea:

https://doi.org/10.1002/art.30452
https://repository.urosario.edu.co/handle/10336/22966

Palabra clave:

Double stranded DNA antibody
Phosphatase
PPP2CA protein
Ribonucleoprotein antibody
Unclassified drug
Adult
African American
Allele
Article
Asian
Controlled study
Disease predisposition
Ethnic difference
European American
Female
Gene expression
Genetic association
Genetic polymorphism
Genetic transcription
Genetic variability
Genotype
Haplotype
Hispanic
Human
Intron
Kidney disease
Major clinical study
Male
Microarray analysis
Priority journal
Real time polymerase chain reaction
Risk assessment
Single nucleotide polymorphism
Systemic lupus erythematosus
T lymphocyte
Adolescent
Adult
Alleles
Asian Continental Ancestry Group
European Continental Ancestry Group
Female
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Haplotypes
Hispanic Americans
Humans
Interleukin-2
Male
Middle Aged
Protein Phosphatase 2
T-Lymphocytes
Systemic
Genetic
Lupus Erythematosus
Polymorphism

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