High transcript levels of vitamin D receptor are correlated with higher mRNA expression of human beta defensins and IL-10 in Mucosa of HIV-1-exposed seronegative individuals

Vitamin D (VitD) is an endogenous immunomodulator that could protect from HIV-1 infection reducing immune activation and inducing the expression of anti-HIV-1 peptides. To establish a correlation between VitD and natural resistance to HIV-1 infection, a case-control study using blood and mucosa samp...

Full description

Autores:

Aguilar-Jiménez W.
Zapata Builes, Wildeman
Caruz A.
Rugeles M.T.

Tipo de recurso:

Article of journal

Fecha de publicación:

2013

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/41889

Acceso en línea:

https://doi.org/10.17533/udea.iatreia.v29n4a06
https://revistas.ucr.ac.cr/index.php/aie/article/view/28679
https://hdl.handle.net/20.500.12494/41889

Palabra clave:

beta defensin 2
beta defensin 3
interleukin 10
interleukin 1beta
messenger RNA
transforming growth factor beta
tumor necrosis factor alpha
vitamin D receptor
adult
article
case control study
controlled study
cross-sectional study
enzyme linked immunosorbent assay
exposure
female
gene expression
genital mucosa
human
Human immunodeficiency virus 1 infection
human tissue
major clinical study
male
mouth mucosa
mucosa
peripheral blood mononuclear cell
reverse transcription polymerase chain reaction
upregulation
vitamin blood level
Adult
beta-Defensins
Cross-Sectional Studies
Cytokines
Disease Resistance
Female
HIV Infections
HIV Seronegativity
HIV-1
Humans
Interleukin-10
Male
Mouth Mucosa
Mucous Membrane
Receptors
Calcitriol
RNA
Messenger
Transcription
Genetic
Vitamin D
Young Adult

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License

http://purl.org/coar/access_right/c_14cb