Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population

Fetal hemoglobin (HbF) is a determining factor for the development of sickle cell anemia. High HbF levels lower the intensity of symptoms of this disease. HbF levels can vary in patients with sickle cell anemia and individuals without the disease.

Autores:
Fong Reales, Cristian javier
Mendoza Y.
Barreto G.
Tipo de recurso:
Article of journal
Fecha de publicación:
2023
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/51025
Acceso en línea:
https://doi.org/10.1590/1678-4685-gmb-2019-0076
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083893639&doi=10.1590%2f1678-4685-gmb-2019-0076&partnerID=40&md5=5561adcca39ee670ec62d132e370bb4a
https://hdl.handle.net/20.500.12494/51025
Palabra clave:
ARTICLE
COLOMBIAN
CHROMOSOME
G GAMMA GLOBIN GENE
GENE
GENE FREQUENCY
GENETIC VARIABILITY
HEMOGLOBIN F
HUMAN
MAJOR CLINICAL STUDY
MULTICENTER STUDY
PROMOTER REGION
PROTEIN EXPRESSION
SICKLE CELL ANEMIA
SINGLE NUCLEOTIDE POLYMORPHISM
Rights
openAccess
License
http://purl.org/coar/access_right/c_abf2
id COOPER2_f3e2b58ba6acd39ed7ff92314aba5272
oai_identifier_str oai:repository.ucc.edu.co:20.500.12494/51025
network_acronym_str COOPER2
network_name_str Repositorio UCC
repository_id_str
spelling Fong Reales, Cristian javierMendoza Y.Barreto G.2023-05-24T16:32:13Z2023-05-24T16:32:13Z22/04/2020https://doi.org/10.1590/1678-4685-gmb-2019-0076https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083893639&doi=10.1590%2f1678-4685-gmb-2019-0076&partnerID=40&md5=5561adcca39ee670ec62d132e370bb4a14154757https://hdl.handle.net/20.500.12494/51025Fong Reales Cristian javier,Mendoza Y.,Barreto G..Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population.Genetics And Molecular Biology. 2020. 43. (2): e20190076Fetal hemoglobin (HbF) is a determining factor for the development of sickle cell anemia. High HbF levels lower the intensity of symptoms of this disease. HbF levels can vary in patients with sickle cell anemia and individuals without the disease.0000-0003-1864-2186cristian.fongr@campusucc.edu.coe20190076Brazilian Journal of GeneticsARTICLECOLOMBIANCHROMOSOMEG GAMMA GLOBIN GENEGENEGENE FREQUENCYGENETIC VARIABILITYHEMOGLOBIN FHUMANMAJOR CLINICAL STUDYMULTICENTER STUDYPROMOTER REGIONPROTEIN EXPRESSIONSICKLE CELL ANEMIASINGLE NUCLEOTIDE POLYMORPHISMGenetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian populationArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionGenetics And Molecular Biologyinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Publication20.500.12494/51025oai:repository.ucc.edu.co:20.500.12494/510252024-08-20 16:20:07.14metadata.onlyhttps://repository.ucc.edu.coRepositorio Institucional Universidad Cooperativa de Colombiabdigital@metabiblioteca.com
dc.title.spa.fl_str_mv Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population
title Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population
spellingShingle Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population
ARTICLE
COLOMBIAN
CHROMOSOME
G GAMMA GLOBIN GENE
GENE
GENE FREQUENCY
GENETIC VARIABILITY
HEMOGLOBIN F
HUMAN
MAJOR CLINICAL STUDY
MULTICENTER STUDY
PROMOTER REGION
PROTEIN EXPRESSION
SICKLE CELL ANEMIA
SINGLE NUCLEOTIDE POLYMORPHISM
title_short Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population
title_full Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population
title_fullStr Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population
title_full_unstemmed Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population
title_sort Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population
dc.creator.fl_str_mv Fong Reales, Cristian javier
Mendoza Y.
Barreto G.
dc.contributor.author.none.fl_str_mv Fong Reales, Cristian javier
Mendoza Y.
Barreto G.
dc.subject.spa.fl_str_mv ARTICLE
COLOMBIAN
CHROMOSOME
G GAMMA GLOBIN GENE
GENE
GENE FREQUENCY
GENETIC VARIABILITY
HEMOGLOBIN F
HUMAN
MAJOR CLINICAL STUDY
MULTICENTER STUDY
PROMOTER REGION
PROTEIN EXPRESSION
SICKLE CELL ANEMIA
SINGLE NUCLEOTIDE POLYMORPHISM
topic ARTICLE
COLOMBIAN
CHROMOSOME
G GAMMA GLOBIN GENE
GENE
GENE FREQUENCY
GENETIC VARIABILITY
HEMOGLOBIN F
HUMAN
MAJOR CLINICAL STUDY
MULTICENTER STUDY
PROMOTER REGION
PROTEIN EXPRESSION
SICKLE CELL ANEMIA
SINGLE NUCLEOTIDE POLYMORPHISM
description Fetal hemoglobin (HbF) is a determining factor for the development of sickle cell anemia. High HbF levels lower the intensity of symptoms of this disease. HbF levels can vary in patients with sickle cell anemia and individuals without the disease.
publishDate 2023
dc.date.accessioned.none.fl_str_mv 2023-05-24T16:32:13Z
dc.date.available.none.fl_str_mv 2023-05-24T16:32:13Z
dc.date.issued.none.fl_str_mv 22/04/2020
dc.type.none.fl_str_mv Artículo
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.coarversion.none.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/article
dc.type.redcol.none.fl_str_mv http://purl.org/redcol/resource_type/ART
dc.type.version.none.fl_str_mv info:eu-repo/semantics/publishedVersion
format http://purl.org/coar/resource_type/c_6501
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.1590/1678-4685-gmb-2019-0076
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083893639&doi=10.1590%2f1678-4685-gmb-2019-0076&partnerID=40&md5=5561adcca39ee670ec62d132e370bb4a
dc.identifier.issn.spa.fl_str_mv 14154757
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12494/51025
dc.identifier.bibliographicCitation.spa.fl_str_mv Fong Reales Cristian javier,Mendoza Y.,Barreto G..Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population.Genetics And Molecular Biology. 2020. 43. (2): e20190076
url https://doi.org/10.1590/1678-4685-gmb-2019-0076
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083893639&doi=10.1590%2f1678-4685-gmb-2019-0076&partnerID=40&md5=5561adcca39ee670ec62d132e370bb4a
https://hdl.handle.net/20.500.12494/51025
identifier_str_mv 14154757
Fong Reales Cristian javier,Mendoza Y.,Barreto G..Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population.Genetics And Molecular Biology. 2020. 43. (2): e20190076
dc.relation.ispartofjournal.spa.fl_str_mv Genetics And Molecular Biology
dc.rights.accessrights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.coar.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
rights_invalid_str_mv http://purl.org/coar/access_right/c_abf2
dc.format.extent.spa.fl_str_mv e20190076
dc.publisher.spa.fl_str_mv Brazilian Journal of Genetics
institution Universidad Cooperativa de Colombia
repository.name.fl_str_mv Repositorio Institucional Universidad Cooperativa de Colombia
repository.mail.fl_str_mv bdigital@metabiblioteca.com
_version_ 1814247021651951616

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