HIV-1-exposed seronegative individuals show alteration in TLR expression and pro-inflammatory cytokine production ex vivo: An innate immune quiescence status?

Pattern recognition receptors (PRRs) are involved in direct recognition of viruses, promoting cellular activation and the production of pro-inflammatory cytokines. However, despite the reduced systemic immune activation described in HIV-1-exposed seronegatives (HESNs), few studies have focused on de...

Full description

Autores:

Hernández López, Juan Carlos
St Laurent G.
Urcuqui-Inchima S.

Tipo de recurso:

Article of journal

Fecha de publicación:

2016

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/41395

Acceso en línea:

https://doi.org/10.1007/s13399-020-00618-z
https://bmcplantbiol.biomedcentral.com/articles/10.1186/s12870-019-1735-9
https://hdl.handle.net/20.500.12494/41395

Palabra clave:

caspase recruitment domain protein 15
interleukin 10
interleukin 18
interleukin 1beta
interleukin 6
messenger RNA
pattern recognition receptor
retinoic acid inducible protein I
toll like receptor
toll like receptor 2
toll like receptor 4
toll like receptor 8
tumor necrosis factor alpha
autacoid
caspase recruitment domain protein 15
cytokine
DDX58 protein
human
DEAD box protein
Human immunodeficiency virus antibody
NOD2 protein
human
retinoic acid inducible protein I
toll like receptor
adult
Article
clinical article
cohort analysis
controlled study
cytokine production
dendritic cell
ex vivo study
female
human
Human immunodeficiency virus 1
Human immunodeficiency virus 1 infection
innate immunity
male
monocyte
nonhuman
pathogenesis
peripheral blood mononuclear cell
priority journal
protein blood level
protein expression
protein function
blood
cell culture
genetics
Human immunodeficiency virus infection
immunology
immunomodulation
metabo

Rights

closedAccess

License

http://purl.org/coar/access_right/c_14cb