In vitro and in vivo evaluation of 2-aminoalkanol and 1,2-alkanediamine derivatives against Strongyloides venezuelensis

Background: Strongyloidiasis is a parasitic disease widely present in tropical and subtropical areas. Strongyloides stercoralis represents the main species that infects human beings. Ivermectin is the current drug of choice; however, issues related with treatment failure in patients with diabetes or...

Full description

Autores:

Legarda-Ceballos A.L.
López-Abán J.
Del Olmo E.
Escarcena R.
Bustos L.A.
Rojas Caraballo, Jose vicente
Vicente B.
Fernández-Soto P.
San Feliciano A.
Muro A.

Tipo de recurso:

Article of journal

Fecha de publicación:

2023

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/49557

Acceso en línea:

https://doi.org/10.1186/s13071-016-1648-5
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84976471071&doi=10.1186%2fs13071-016-1648-5&partnerID=40&md5=21a6d13bef8deac76efc3eace827144a
https://hdl.handle.net/20.500.12494/49557

Palabra clave:

[2 (BUTYLAMINO)HEXADECAN 1 OL]
[2 (ETHYLAMINO)HEXADECAN 1 OL]
[TERT BUTYL N (1 AMINODODECAN 2 YL)CARBAMATE]
[TERT BUTYL N (1 AMINOHEXADECAN 2 YL)CARBAMATE]
1,2 ALKANEDIAMINE DERIVATIVE
2 AMINOALKANOL
AMINO ALCOHOLS
AMINOALCOHOL
ANIMAL
ANIMAL CELL
ANIMAL EXPERIMENT
ANIMAL MODEL
ANIMAL TISSUE
ANIMALS
ANTHELMINTIC AGENT
ANTHELMINTICS
ANTINEMATODAL AGENT
ARTICLE
CONTROLLED STUDY
CYTOTOXICITY TEST
CHEMICAL STRUCTURE
CHEMISTRY
DIAMINE
DIAMINES
DRUG EFFECTS
DRUG EFFICACY
DRUG IDENTIFICATION
DRUG SCREENING
DRUG STRUCTURE
EDELFOSINE
FECES ANALYSIS
FEMALE
IN VITRO STUDY
IN VIVO STUDY
IVERMECTIN
LC50
MALE
MICE
MOLECULAR STRUCTURE
MOUSE
NONHUMAN
OUTCOME ASSESSMENT
PARASITOLOGY
RAT
RATS
STRONGYLOIDES
STRONGYLOIDES VENEZUELENSIS
STRONGYLOIDIASIS
STRUCTURE ACTIVITY RELATION
STRUCTURE-ACTIVITY RELATIONSHIP
UNCLASSIFIED DRUG
XTT ASSAY

Rights

openAccess

License

http://purl.org/coar/access_right/c_abf2