Absence of the CHEK2 c.1100delC mutation in familial breast and ovarian cancer in Colombia: a case-control study
Background: BRCA1 and BRCA2 have been identified as high-penetrance breast cancer predisposition genes, but they only account for a small fraction of the inherited component of breast cancer. To explain the remaining cases, a polygenic model with a large number of low- to moderate-penetrance genes h...
- Autores:
-
Cifuentes Cardona, Laura Fernanda
Rivera Herrera, Ana Lucia
Gil Vera, JA
Barreto, Guillermo
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2018
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/16000
- Acceso en línea:
- https://doi.org/10.12688/f1000research.13368.1
https://hdl.handle.net/20.500.12494/16000
- Palabra clave:
- CHEK2
Familial breast and ovarian cancer
Colombia
CHEK2 c.1100delC
Moderate-penetrance
CHEK2
Familial breast and ovarian cancer
Colombia
CHEK2 c.1100delC
Moderate-penetrance
- Rights
- openAccess
- License
- Atribución – No comercial – Sin Derivar