Venomic, Transcriptomic, and Bioactivity Analyses of Pamphobeteus verdolaga Venom Reveal Complex Disulfide-Rich Peptides That Modulate Calcium Channels

Pamphobeteus verdolaga is a recently described Theraphosidae spider from the Andean region of Colombia. Previous reports partially characterized its venom profile. In this study, we conducted a detailed analysis that includes reversed-phase high-performance liquid chromatography (rp-HPLC), calcium i...

Full description

Autores:

Vargas Muñoz, Leidy Johana
Vargas Muñoz, Leidy Johana
Estrada Gómez, Sebastián
Caldas Cardoso, Fernanda
Quintana Castillo, Juan Carlos
Saldarriaga Córdoba, Mónica María
Arenas Gómez, Claudia Marcela
Pineda, Sandy Steffany

Tipo de recurso:

Article of journal

Fecha de publicación:

2019

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/15916

Acceso en línea:

https://hdl.handle.net/20.500.12494/15916

Palabra clave:

theraphosidae
Pamphobeteus
Peptides
Disulfide-rich peptide (DRP)
Inhibitory cysteine knot (ICK)
Venomics
Transcriptome
Ion channels

Rights

openAccess

License

Atribución – No comercial – Sin Derivar