HIV type 1 infection up-regulates TLR2 and TLR4 expression and function in vivo and in vitro

Toll-like receptors (TLRs) play a critical role in innate immunity against pathogens. Their stimulation induces the activation of NF-?B, an important inducer of HIV-1 replication. In recent years, an increasing number of studies using several cells types from HIV-infected patients indicate that TLRs...

Full description

Autores:
Hernández López, Juan Carlos
Stevenson M.
Latz E.
Urcuqui-Inchima S.
Tipo de recurso:
Article of journal
Fecha de publicación:
2012
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/41726
Acceso en línea:
https://doi.org/10.15446/anpol.v31n94.78239
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85053407586&doi=10.7203%2fCIRIEC-E.93.10327&partnerID=40&md5=bf4e34a3b306679b0594288956a8839c
https://hdl.handle.net/20.500.12494/41726
Palabra clave:
abacavir
amprenavir
B7 antigen
beta actin
CD123 antigen
CD14 antigen
CD4 antigen
cytokine
didanosine
efavirenz
fosamprenavir
immunoglobulin enhancer binding protein
interleukin 1beta
interleukin 6
lamivudine
lopinavir
messenger RNA
nelfinavir
nevirapine
saquinavir
stavudine
toll like receptor 2
toll like receptor 4
tumor necrosis factor alpha
zidovudine
acquired immune deficiency syndrome
adolescent
adult
article
CD4+ T lymphocyte
cell subpopulation
clinical article
controlled study
cytokine production
ex vivo study
female
gene expression regulation
highly active antiretroviral therapy
human
human cell
Human immunodeficiency virus 1
Human immunodeficiency virus 1 infection
Human immunodeficiency virus infected patient
immune response
immunomodulation
in vitro study
in vivo study
inflammation
innate immunity
macrophage
male
monocyte
myeloid dendritic cell
nonhuman
peripheral blood mononuclear cell
plasmacytoid dendritic cell
priori
Rights
closedAccess
License
http://purl.org/coar/access_right/c_14cb