Human macrophages differentiated in the presence of vitamin D3restrict dengue virus infection and innate responses by downregulating mannose receptor expression

Background: Severe dengue disease is associated with high viral loads and overproduction of pro-inflammatory cytokines, suggesting impairment in the control of dengue virus (DENV) and the mechanisms that regulate cytokine production. Vitamin D3has been described as an important modulator of immune r...

Full description

Autores:

Arboleda Alzate, J. F.
Rodenhuis Zybert, I. A.
Hernández López, Juan Carlos
Smit, J. M.
Urcuqui Inchima, S.

Tipo de recurso:

Article of journal

Fecha de publicación:

2023

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/49624

Acceso en línea:

https://doi.org/10.1371/journal.pntd.0005904
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85032668736&doi=10.1371%2fjournal.pntd.0005904&partnerID=40&md5=fc47c7f8ca16478c0af00e24fff7258b
https://hdl.handle.net/20.500.12494/49624

Palabra clave:

ADULT
ANIMAL
ANIMALS
ARTICLE
BLOOD DONOR
BLOOD DONORS
CELL DIFFERENTIATION
CELL LINE
CELL SURFACE RECEPTOR
COLECALCIFEROL
CULICIDAE
CHOLECALCIFEROL
DENGUE VIRUS
DOWN REGULATION
DOWN-REGULATION
DRUG EFFECTS
ENZYME LINKED IMMUNOSORBENT ASSAY
FEMALE
FLOW CYTOMETRY
GENE EXPRESSION
GENE EXPRESSION REGULATION
GENETICS
HUMAN
HUMANS
IMMUNE RESPONSE
IMMUNITY, INNATE
INFLAMMATION
INNATE IMMUNITY
INTERLEUKIN 10
INTERLEUKIN 1BETA
INTERLEUKIN 6
LECTIN
LECTINS, C-TYPE
MACROPHAGE
MACROPHAGES
MALE
MANNOSE BINDING LECTIN
MANNOSE RECEPTOR
MANNOSE-BINDING LECTINS
METABOLISM
MOSQUITO
NONHUMAN
PHYSIOLOGY
REAL TIME POLYMERASE CHAIN REACTION
RECEPTORS, CELL S
REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION
TUMOR NECROSIS FACTOR
VIROLOGY
VIRUS INFECTION
VIRUS PARTICLE
VIRUS REPLICATION

Rights

openAccess

License

http://purl.org/coar/access_right/c_abf2