Identification of innate immune antiretroviral factors during in vivo and in vitro exposure to HIV-1

Defensins, RNases and cytokines are present at mucosal barriers, main ports of HIV entry, and are potential mediators of the resistant phenotype exhibited by HIV-1-exposed seronegative individuals (HESN) during sexual exposure. We aimed to determine the role of soluble factors in natural resistance...

Full description

Autores:

Zapata Builes, Wildeman
Aguilar-Jiménez W.
Feng Z.
Weinberg A.
Russo A.
Potenza N.
Estrada H.
Rugeles M.T.

Tipo de recurso:

Article of journal

Fecha de publicación:

2016

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/41505

Acceso en línea:

https://doi.org/10.1016/j.vetmic.2016.12.039
https://hdl.handle.net/20.500.12494/41505

Palabra clave:

angiogenin
beta defensin 2
beta defensin 3
macrophage inflammatory protein 1beta
maraviroc
messenger RNA
n [4 [[[6,7 dihydro 2 (4 methylphenyl) 5h benzocyclohepten 8 yl]carbonyl]amino]benzyl] n,n dimethyl 2h tetrahydropyran 4 aminium chloride
neutrophil peptide 1
plerixafor
protein
RANTES
ribonuclease
unclassified drug
zidovudine
immunologic factor
adult
antiviral activity
Article
CD4+ T lymphocyte
controlled study
dose response
human
Human immunodeficiency virus 1
Human immunodeficiency virus 1 infection
in vitro study
in vivo study
innate immunity
life cycle
major clinical study
mouth mucosa
polymerase chain reaction
priority journal
protein analysis
protein expression
protein function
quantitative analysis
reverse transcription
sexual intercourse
uterine cervix mucosa
vagina mucosa
viral tropism
virus entry
virus infectivity
virus inhibition
virus load
virus replication
virus resistance
virus strain
adolescent
disease resistance
fema

Rights

closedAccess

License

http://purl.org/coar/access_right/c_14cb