Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population

Fetal hemoglobin (HbF) is a determining factor for the development of sickle cell anemia. High HbF levels lower the intensity of symptoms of this disease. HbF levels can vary in patients with sickle cell anemia and individuals without the disease. The purpose of this study was to identify the geneti...

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Autores:
Fong, Cristian
Mendoza, Yesica
Barreto, Guillermo
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/32912
Acceso en línea:
http://dx.doi.org/10.1590/1678-4685-GMB-2019-0076
https://hdl.handle.net/20.500.12494/32912
Palabra clave:
Sickle cell anemia
Fetal hemoglobin
Gamma globin
Regulation of gene expression
Colombia
Rights
openAccess
License
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