Genetic variants in the G gamma-globin promoter modulate fetal hemoglobin expression in the Colombian population
Fetal hemoglobin (HbF) is a determining factor for the development of sickle cell anemia. High HbF levels lower the intensity of symptoms of this disease. HbF levels can vary in patients with sickle cell anemia and individuals without the disease. The purpose of this study was to identify the geneti...
- Autores:
-
Fong, Cristian
Mendoza, Yesica
Barreto, Guillermo
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2020
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/32912
- Acceso en línea:
- http://dx.doi.org/10.1590/1678-4685-GMB-2019-0076
https://hdl.handle.net/20.500.12494/32912
- Palabra clave:
- Sickle cell anemia
Fetal hemoglobin
Gamma globin
Regulation of gene expression
Colombia
- Rights
- openAccess
- License
- Atribución