High transcript levels of vitamin D receptor are correlated with higher mRNA expression of human beta defensins and IL-10 in Mucosa of HIV-1-exposed seronegative individuals

Vitamin D (VitD) is an endogenous immunomodulator that could protect from HIV-1 infection reducing immune activation and inducing the expression of anti-HIV-1 peptides. To establish a correlation between VitD and natural resistance to HIV-1 infection, a case-control study using blood and mucosa samp...

Full description

Autores:
Aguilar-Jiménez W.
Zapata Builes, Wildeman
Caruz A.
Rugeles M.T.
Tipo de recurso:
Article of journal
Fecha de publicación:
2023
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/49708
Acceso en línea:
https://doi.org/10.1371/journal.pone.0082717
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84891929244&doi=10.1371%2fjournal.pone.0082717&partnerID=40&md5=736f953417b5d443d89682d9d1d1bdbc
https://hdl.handle.net/20.500.12494/49708
Palabra clave:
ADULT
ARTICLE
BETA DEFENSIN 2
BETA DEFENSIN 3
BETA-DEFENSINS
CASE CONTROL STUDY
CONTROLLED STUDY
CROSS-SECTIONAL STUDIES
CROSS-SECTIONAL STUDY
CYTOKINES
DISEASE RESISTANCE
ENZYME LINKED IMMUNOSORBENT ASSAY
EXPOSURE
FEMALE
GENE EXPRESSION
GENITAL MUCOSA
HIV INFECTIONS
HIV SERONEGATIVITY
HIV-1
HUMAN
HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION
HUMAN TISSUE
HUMANS
INTERLEUKIN 10
INTERLEUKIN 1BETA
INTERLEUKIN-10
MAJOR CLINICAL STUDY
MALE
MESSENGER RNA
MOUTH MUCOSA
MUCOSA
MUCOUS MEMBRANE
PERIPHERAL BLOOD MONONUCLEAR CELL
RECEPTORS, CALCITRIOL
REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION
RNA, MESSENGER
TRANSCRIPTION, GENETIC
TRANSFORMING GROWTH FACTOR BETA
TUMOR NECROSIS FACTOR ALPHA
UPREGULATION
VITAMIN BLOOD LEVEL
VITAMIN D
VITAMIN D RECEPTOR
YOUNG ADULT
Rights
openAccess
License
http://purl.org/coar/access_right/c_abf2