Venom from Opisthacanthus elatus scorpion of Colombia, could be more hemolytic and less neurotoxic than thought

We report the first biochemical, biological, pharmacological and partial proteomic characterization studies of the Opisthancanthus elatus venom (Gervais, 1844) from Colombia. The Reverse Phase High-Performance Liquid Chromatography venom profile showed 28 main well-defined peaks, most eluting betwee...

Full description

Autores:

Estrada-Gómez S.
Vargas Muñoz, Leidy Johana
Saldarriaga-Córdoba M.
Quintana Castillo, Juan Carlos

Tipo de recurso:

Article of journal

Fecha de publicación:

2016

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/41414

Acceso en línea:

https://doi.org/10.1016/j.comptc.2018.04.016
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85062630680&doi=10.1186%2fs12985-019-1136-6&partnerID=40&md5=5767cde0dd8645cd8bfab19f2d6f4fc8
https://hdl.handle.net/20.500.12494/41414

Palabra clave:

4 nitro 3 octanoyloxy benzoic acid
benzoic acid
phospholipase A2
scorpion venom
serine proteinase
unclassified drug
hemolytic agent
neurotoxin
scorpion venom
arachnid
biochemistry
DNA fingerprinting
enzyme activity
hydrolysis
mass spectrometry
microbial activity
proteomics
venom
animal experiment
antimicrobial activity
Article
blood clotting
chemical analysis
Colombia
controlled study
enzyme activity
female
hemolysis
human
hydrolysis
molecular weight
mouse
neurotoxicity
nonhuman
Opisthacanthus elatus
reversed phase high performance liquid chromatography
scorpion
tandem mass spectrometry
animal
chemistry
high performance liquid chromatography
scorpion
Colombia
Mammalia
Opisthacanthus
Scorpiones
Animals
Chromatography
High Pressure Liquid
Colombia
Hemolytic Agents
Molecular Weight
Neurotoxins
Scorpion Venoms
Scorpions
Tandem Mass Spectrometry

Rights

closedAccess

License

http://purl.org/coar/access_right/c_14cb