Absence of the CHEK2 c.1100delC mutation in familial breast and ovarian cancer in Colombia: a case-control study
Background: BRCA1 and BRCA2 have been identified as high-penetrance breast cancer predisposition genes, but they only account for a small fraction of the inherited component of breast cancer. To explain the remaining cases, a polygenic model with a large number of low-to moderate-penetrance genes ha...
- Autores:
-
Rivera Herrera, Ana Lucia
Cifuentes Cardona, Laura Fernanda
Gil Vera, Ja
Barreto, Guillermo
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2018
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/41754
- Acceso en línea:
- https://doi.org/10.15649/cuidarte.v4i1.10
https://hdl.handle.net/20.500.12494/41754
- Palabra clave:
- checkpoint kinase 2
adult
age
allele specific polymerase chain reaction
Article
breast cancer
cancer risk
cancer screening
cancer susceptibility
CHEK2 gene
clinical feature
cohort analysis
Colombia
controlled study
cross-sectional study
female
gene function
gene mutation
genetic screening
genotype
heterozygote
homozygote
human
major clinical study
ovary cancer
risk factor
sex
social status
- Rights
- closedAccess
- License
- http://purl.org/coar/access_right/c_14cb