Antiplasmodial effect of the venom of Crotalus durissus cumanensis, crotoxin complex and Crotoxin B

The antiplasmodial activity of phospholipases A2 (PLA2) isolated from different animals has been studied. We explored the in vitro anti Plasmodium falciparum effect of a fraction containing crotoxin, Crotoxin B and whole venom of the rattlesnake Crotalus durissus cumanensis. Fraction II (crotoxin co...

Full description

Autores:

Quintana Castillo, Juan Carlos
Chacón A.M.
Vargas L.
Segura C.
Gutiérrez J.M.
Alarcón J.C.

Tipo de recurso:

Article of journal

Fecha de publicación:

2012

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/41413

Acceso en línea:

https://doi.org/10.1016/j.bjid.2018.07.010
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85063934736&doi=10.1002%2fceat.201800456&partnerID=40&md5=2452389a72c02f542f6afb65a00fb8b5
https://hdl.handle.net/20.500.12494/41413

Palabra clave:

crotoxin
crotoxin b
crotoxin complex
snake venom
unclassified drug
antimalarial agent
malaria
parasite
snake
toxicity
venom
acute toxicity
amino acid sequence
animal experiment
antimalarial activity
article
concentration response
controlled study
Crotalus
crotalus durissus cumanensis
drug cytotoxicity
drug effect
drug purification
drug screening
gel permeation chromatography
human
human cell
in vitro study
LD 50
lethality
mouse
neurotoxicity
nonhuman
peripheral blood mononuclear cell
Plasmodium falciparum
reversed phase high performance liquid chromatography
Amino Acid Sequence
Animals
Antimalarials
Cell Survival
Cells
Cultured
Crotalus
Crotoxin
Humans
Leukocytes
Mononuclear
Mice
Molecular Sequence Data
Plasmodium falciparum
Survival Analysis
Venoms
Animalia
Crotalus durissus cumanensis
Mus
Plasmodium falciparum

Rights

closedAccess

License

http://purl.org/coar/access_right/c_14cb