Molecular characterization of dengue virus reveals regional diversification of serotype 2 in Colombia

Dengue is hyperendemic in Colombia, where a cyclic behavior of serotype replacement leading to periodic epidemics has been observed for decades. This level of endemicity favors accumulation of dengue virus genetic diversity and could be linked to disease outcome. To assess the genetic diversity of d...

Full description

Autores:
Laiton-Donato K.
Alvarez D.A.
Peláez-Carvajal D.
Mercado M.
Ajami N.J.
Bosch I.
Usme Ciro, José Aldemar
Tipo de recurso:
Article of journal
Fecha de publicación:
2019
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/41838
Acceso en línea:
https://doi.org/10.16925/ra.v17i31.1096
https://hdl.handle.net/20.500.12494/41838
Palabra clave:
adolescent
adult
Article
child
clinical article
Colombia
Dengue virus
envelope gene
female
gene sequence
genetic variability
genotype
geography
human
male
middle aged
nonhuman
nucleotide sequence
phylogeny
retrospective study
severe dengue
virus characterization
virus gene
virus isolation
biobank
blood
dengue
Dengue virus
genetic variation
genetics
genotype
high throughput sequencing
preschool child
serotype
virology
young adult
virus envelope protein
virus RNA
Adolescent
Adult
Biological Specimen Banks
Child
Child
Preschool
Colombia
Dengue
Dengue Virus
Female
Genetic Variation
Genotype
High-Throughput Nucleotide Sequencing
Humans
Male
Middle Aged
Phylogeny
Retrospective Studies
RNA
Viral
Serogroup
Viral Envelope Proteins
Young Adult
Rights
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License
http://purl.org/coar/access_right/c_14cb