Efficacy of the benznidazole+posaconazole combination therapy in parasitemia reduction: An experimental murine model of acute chagas

Introduction: Benznidazole (BZL) and Nifurtimox (NFX) are the pharmacological treatment for acute phase Chagas Disease (CD); however, therapy resistance and residual mortality development remain important unresolved issues. Posaconazole (POS) has shown a trypanocidal effect in vivo and in vitro. Thu...

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Autores:
Echeverría L.E.
González C.I.
Hernandez J.C.M.
Díaz M.L.
Nieto Pico, Javier Eduardo
López-Romero L.A.
Rivera J.D.
Suárez E.U.
Ochoa S.A.G.
Rojas L.Z.
Morillo C.A.
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad Cooperativa de Colombia
Repositorio:
Repositorio UCC
Idioma:
OAI Identifier:
oai:repository.ucc.edu.co:20.500.12494/42289
Acceso en línea:
https://doi.org/10.3233/NRE-2010-0614
https://hdl.handle.net/20.500.12494/42289
Palabra clave:
Wistar rats
Chagas Disease
Trypanocidal
Benznidazole and Posaconazole
Rights
closedAccess
License
http://purl.org/coar/access_right/c_14cb