In vitro antiplasmodial activity of phospholipases A2 and a phospholipase homologue isolated from the venom of the snake Bothrops asper

The antimicrobial and antiparasite activity of phospholipase A2 (PLA2) from snakes and bees has been extensively explored. We studied the antiplasmodial effect of the whole venom of the snake Bothrops asper and of two fractions purified by ion-exchange chromatography: one containing catalytically-ac...

Full description

Autores:

Quintana Castillo, Juan carlos
Vargas L.J.
Segura C.
Gutiérrez J.M.
Pérez J.C.A.

Tipo de recurso:

Article of journal

Fecha de publicación:

2023

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/50957

Acceso en línea:

https://doi.org/10.3390/toxins4121500
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84873022885&doi=10.3390%2ftoxins4121500&partnerID=40&md5=a1e2a8eccab1ee1b06075da88b37bcd0
https://hdl.handle.net/20.500.12494/50957

Palabra clave:

ACUTE TOXICITY
AMINO ACID SEQUENCE
ANIMALS
ANTIMALARIAL ACTIVITY
ANTIPLASMODIAL ACTIVITY
ANTIPROTOZOAL AGENTS
ARTICLE
BOTHROPS
BOTHROPS ASPER
CELL FRACTIONATION
CELL SURVIVAL
CELLS, CULTURED
CONTROLLED STUDY
CROTALID VENOMS
CYTOTOXICITY
DRUG ACTIVITY
ENZYME ACTIVE SITE
ENZYME ACTIVITY
ERYTHROCYTES
HEMOLYSIS
HUMANS
IC 50
IN VITRO STUDY
ION EXCHANGE CHROMATOGRAPHY
LD 50
LETHAL DOSE 50
LETHALITY
LEUKOCYTES, MONONUCLEAR
MICE
MOLECULAR SEQUENCE DATA
NONHUMAN
NUCLEOTIDE SEQUENCE
PERIPHERAL BLOOD MONONUCLEAR CELL
PHOSPHOLIPASE
PHOSPHOLIPASE A2
PHOSPHOLIPASES
PLASMODIUM FALCIPARUM
SEQUENCE ALIGNMENT
SNAKE
SNAKE VENOM
TOXICITY TESTING

Rights

openAccess

License

http://purl.org/coar/access_right/c_abf2