Efficacy of the benznidazole+posaconazole combination therapy in parasitemia reduction: An experimental murine model of acute chagas

Introduction: Benznidazole (BZL) and Nifurtimox (NFX) are the pharmacological treatment for acute phase Chagas Disease (CD); however, therapy resistance and residual mortality development remain important unresolved issues. Posaconazole (POS) has shown a trypanocidal effect in vivo and in vitro. Thu...

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Autores:

Echeverría L.E.
González C.I.
Hernandez J.C.M.
Díaz M.L.
Nieto Pico, Javier eduardo
López-Romero L.A.
Rivera J.D.
Suárez E.U.
Ochoa S.A.G.
Rojas L.Z.
Morillo C.A.

Tipo de recurso:

Article of journal

Fecha de publicación:

2023

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/51041

Acceso en línea:

https://doi.org/10.1590/0037-8682-0477-2019
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079336125&doi=10.1590%2f0037-8682-0477-2019&partnerID=40&md5=d6edadee009fccda59130dc0f635b86b
https://hdl.handle.net/20.500.12494/51041

Palabra clave:

BENZNIDAZOLE AND POSACONAZOLE
CHAGAS DISEASE
TRYPANOCIDAL
WISTAR RATS

Rights

openAccess

License

http://purl.org/coar/access_right/c_abf2