Mutations of the CHEK2 gene in patients with cancer and their presence in the Latin American population

Background: CHEK2 (Checkpoint Kinase 2) encodes CHK2, a serine/threonine kinase involved in maintaining the G1/S and G2/M checkpoints and repair of double-strand DNA breaks via homologous recombination. Functions of CHK2 include the prevention of damaged

• Autores: Guauque Olarte, Sandra Milena; Rivera Herrera, Ana Lucia; Cifuentes Cardona, Laura Fernanda
• Tipo de recurso: Article of journal
• Fecha de publicación: 2016
• Institución: Universidad Cooperativa de Colombia
• Repositorio: Repositorio UCC
• OAI Identifier: oai:repository.ucc.edu.co:20.500.12494/41851
• Acceso en línea: https://doi.org/10.17081/just.3.27.328; https://hdl.handle.net/20.500.12494/41851
• Palabra clave: CHEK2; CHK2; cancer; Latin America; databases; mutations; CHEK2*1100delC; genomics
• Rights: closedAccess
• License: http://purl.org/coar/access_right/c_14cb