Mutations of the CHEK2 gene in patients with cancer and their presence in the Latin American population
Background: CHEK2 (Checkpoint Kinase 2) encodes CHK2, a serine/threonine kinase involved in maintaining the G1/S and G2/M checkpoints and repair of double-strand DNA breaks via homologous recombination. Functions of CHK2 include the prevention of damaged
- Autores:
-
Guauque Olarte, Sandra Milena
Rivera Herrera, Ana Lucia
Cifuentes Cardona, Laura Fernanda
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2016
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/41851
- Palabra clave:
- CHEK2
CHK2
cancer
Latin America
databases
mutations
CHEK2*1100delC
genomics
- Rights
- closedAccess
- License
- http://purl.org/coar/access_right/c_14cb